Spravato® in Omaha, NE
Do I Qualify for Spravato®?
Spravato® is designed for adults living with treatment-resistant depression. It may be recommended when standard depression medicines have not worked well enough. A full psychiatric evaluation at ORIGEN Healthcare decides whether it is the right and safe option for you.
- FDA-approved for adults
- Given and monitored in our clinic
- Psychiatric evaluation first
Quick self-check
Tick what is true for you. This is not a diagnosis: it helps you decide whether to ask for an evaluation.
Tick the statements that fit you.
If you are thinking about suicide or self-harm, call or text 988, or call 911 in an emergency.
What treatment-resistant depression means
Treatment-resistant depression happens when a person has tried two or more antidepressant medications without enough improvement. Spravato® is not a first-line treatment: it is used when other medicines do not work well enough, and it is usually used together with a regular antidepressant.
Your safety at every visit
Spravato® is for adults, and every dose is given and watched in our clinic.
- Spravato® is only given in a certified clinic through the FDA safety program called REMS.
- Your blood pressure is checked before and after each dose.
- You stay with us for at least two hours after the nasal spray, until our team says you are ready to go.
- Arrange for someone to drive you home, and avoid driving until the next day after a full night’s sleep.
Common side effects
Dizziness, sleepiness, nausea, headache, higher blood pressure and feeling disconnected or dream-like. They usually start soon after the dose and ease within a few hours.
Serious risks to know
Strong sedation, dissociation, breathing problems, a risk of misuse, and, as with other antidepressants, suicidal thoughts in some young people. These are why every dose is given and watched in the clinic.
Who should not take it
People with an aneurysm or abnormal blood vessel connection (in the aorta, brain or limbs), a history of bleeding in the brain, or an allergy to esketamine or ketamine. Your provider checks this at the evaluation.
Before each dose: no food for at least 2 hours and no drinks for at least 30 minutes. This is a summary of the FDA Medication Guide for Spravato®. Ask your provider for the full guide, or read the Medication Guide.
Indications for Spravato®
Spravato® is approved by the FDA for two uses in adults:
Treatment-resistant depression
Adults with major depressive disorder who have tried two or more antidepressants without enough improvement. Spravato® can be used on its own or together with an oral antidepressant.
Depression with acute suicidal thoughts or behavior
Depressive symptoms in adults with major depressive disorder with acute suicidal thoughts or behavior, used together with an oral antidepressant and under close medical care.
Spravato® has not been shown to prevent suicide or reduce suicidal thoughts or behavior, and it does not replace hospital care when that is needed.
If you are thinking about suicide or self-harm, call or text 988 (Suicide and Crisis Lifeline), or call 911 in an emergency.
What the evaluation looks at
- Your symptoms and how long they have lasted
- Your medical history and blood pressure
- The depression medicines you have tried before
- Whether Spravato® is the right and safe option for you
Plan your Spravato® care
Questions patients ask
Who qualifies for Spravato treatment?
Spravato therapy is typically recommended for patients who have tried multiple antidepressant medications without significant improvement. A psychiatric evaluation is required to determine if the treatment is appropriate.
Is Spravato® treatment safe?
Spravato® is administered in a certified medical clinic under the supervision of trained healthcare providers. Each treatment session is carefully monitored, and patients remain in the clinic for observation to ensure safety and comfort during and after the treatment.
Your provider
Nazira Usmanova, DNP
Doctor of Nursing Practice, Board-Certified Nurse Practitioner, with more than 14 years of clinical experience. She sees children from age 2, teens and adults, and speaks English, Russian and Farsi.
- Psychiatric Mental Health NP (PMHNP-BC)
- Pediatric NP (CPNP-PC)
- Adult-Gerontology NP (AGNP-BC)
“True healing comes from listening, understanding, and walking alongside my patients in their journey to wellness.”
Nazira Usmanova
Insurance we work with
We work with most major insurance plans. Coverage depends on your plan and the service, so our team checks your benefits with you before your visit.
Insurance and costs
Take the first step toward feeling better
You don’t have to figure it out alone. Tell us what is going on, and our care team will call you to find the right visit.