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Spravato® in Omaha, NE

Spravato Treatment in Omaha, NE for Treatment-Resistant Depression

If traditional antidepressants haven’t worked, Spravato® treatment may help. ORIGEN Healthcare in Omaha offers medically supervised Spravato therapy for adults struggling with treatment-resistant depression.

  • FDA-approved for adults
  • Given and monitored in our clinic
  • Psychiatric evaluation first
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The Spravato treatment room at ORIGEN Healthcare: two reclining chairs, floor lamps and soft window light
Observation time per session
at least two hours
Starting schedule
twice per week for the first phase, then less often
Prior antidepressants for treatment-resistant depression
two or more
Age group
adults

What is Spravato® treatment?

Spravato® treatment is a new option for adults with treatment-resistant depression. It is an FDA-approved medicine called esketamine. The medicine is given as a nasal spray. It works in a different way than many regular antidepressant medicines and may help improve mood for some patients.

At ORIGEN Healthcare in Omaha, Nebraska, Spravato treatment is given in our clinic under medical supervision. Patients use the nasal spray during their visit, and our team monitors them for at least two hours to make sure they are safe and comfortable.

Spravato therapy is often used when other depression medicines have not worked well. Before starting treatment, patients receive a psychiatric evaluation to see if Spravato is the right option.

During each treatment visit, patients stay in the clinic while our healthcare team monitors their response. Many people with treatment-resistant depression choose Spravato therapy as an advanced treatment option to help improve mood, daily functioning, and overall mental well-being.

Your safety at every visit

Spravato® is for adults, and every dose is given and watched in our clinic.

  • Spravato® is only given in a certified clinic through the FDA safety program called REMS.
  • Your blood pressure is checked before and after each dose.
  • You stay with us for at least two hours after the nasal spray, until our team says you are ready to go.
  • Arrange for someone to drive you home, and avoid driving until the next day after a full night’s sleep.
A Spravato (esketamine) nasal spray device
The Spravato® nasal spray device

Common side effects

Dizziness, sleepiness, nausea, headache, higher blood pressure and feeling disconnected or dream-like. They usually start soon after the dose and ease within a few hours.

Serious risks to know

Strong sedation, dissociation, breathing problems, a risk of misuse, and, as with other antidepressants, suicidal thoughts in some young people. These are why every dose is given and watched in the clinic.

Who should not take it

People with an aneurysm or abnormal blood vessel connection (in the aorta, brain or limbs), a history of bleeding in the brain, or an allergy to esketamine or ketamine. Your provider checks this at the evaluation.

Before each dose: no food for at least 2 hours and no drinks for at least 30 minutes. This is a summary of the FDA Medication Guide for Spravato®. Ask your provider for the full guide, or read the Medication Guide.

Who may qualify for Spravato® treatment?

Spravato® treatment is designed for adults who are living with treatment-resistant depression. It may be recommended when standard depression medicines have not worked well enough.

Adults with major depression who have tried at least two antidepressants without enough relief may qualify. Your psychiatric evaluation decides.

How Spravato® treatment works

Spravato® treatment is given in a safe medical setting. At ORIGEN Healthcare in Omaha, each visit follows a simple and carefully monitored process.

  1. Evaluation & treatment plan

    Before starting Spravato therapy, patients receive a full psychiatric evaluation. Our provider reviews your symptoms, medical history, and previous depression treatments to decide if Spravato treatment is the right option.

  2. Nasal spray administration

    Spravato is given as a nasal spray in the clinic. Patients use the spray during their appointment while our healthcare team guides the process.

  3. Medical monitoring

    After receiving the medication, patients relax in the clinic while our team monitors them. Each session includes at least two hours of observation to ensure safety and comfort.

  4. Ongoing treatment sessions

    Most patients begin treatment twice per week for the first phase. After that, sessions may become less frequent depending on how the patient responds to Spravato therapy.

What to expect during a Spravato® treatment session

Starting a new treatment can feel uncertain. At ORIGEN Healthcare, our goal is to make every Spravato® visit comfortable, safe and supportive for each patient.

Compassionate guidance

Our provider and care team will guide you through each step of the treatment process. We explain how the Spravato nasal spray works and answer any questions so you feel confident and prepared during your visit.

Supervised, secure care

After the medication is administered, you will relax in our clinic while our team monitors you. This observation period helps ensure your safety and comfort throughout the session.

Care designed for you

Every patient’s experience with depression is different. Your treatment plan is personalized and carefully monitored so we can support your progress and help you achieve the best possible results.

Indications for Spravato treatment

Spravato® is approved by the FDA for two uses in adults:

Treatment-resistant depression

Adults with major depressive disorder who have tried two or more antidepressants without enough improvement. Spravato® can be used on its own or together with an oral antidepressant.

Depression with acute suicidal thoughts or behavior

Depressive symptoms in adults with major depressive disorder with acute suicidal thoughts or behavior, used together with an oral antidepressant and under close medical care.

Spravato® has not been shown to prevent suicide or reduce suicidal thoughts or behavior, and it does not replace hospital care when that is needed.

If you are thinking about suicide or self-harm, call or text 988 (Suicide and Crisis Lifeline), or call 911 in an emergency.

Questions patients ask

Does Spravato® treatment work?

Spravato® is FDA-approved for adults with treatment-resistant depression, and for depressive symptoms in adults with major depression with acute suicidal thoughts or behavior. Results differ from person to person. Your provider checks your progress at every stage and talks with you about whether it is helping.

How is Spravato® kept safe?

Spravato® is given only in certified clinics through the FDA safety program (REMS), because it can cause sleepiness, dissociation and a rise in blood pressure. Every dose is taken in our clinic, your blood pressure is checked, and you stay with us for at least two hours until our team says you are ready to go. Your provider goes through the risks and the Medication Guide with you before you start.

Is Spravato® covered by insurance?

Many insurance plans, including some Medicare and Medicaid plans, may cover Spravato® treatment for patients who meet eligibility requirements. Our team at ORIGEN Healthcare helps patients review their insurance coverage and guides them through the approval process whenever possible.

How long does a Spravato treatment session take?

A typical Spravato® treatment visit lasts at least two hours. After the medication is administered, patients relax comfortably in our clinic while our team monitors them to ensure everything goes smoothly.

Is it hard to get prescribed Spravato?

Spravato® is typically recommended for individuals with treatment-resistant depression, meaning other medications have not provided enough relief. Our provider will conduct a comprehensive psychiatric evaluation to determine if Spravato is the right and safe treatment option for you.

How much does Spravato treatment cost?

The cost of Spravato treatment can vary depending on insurance coverage and individual treatment plans. Because every patient’s situation is different, we encourage you to contact ORIGEN Healthcare directly so our team can review your options and provide accurate information about coverage and pricing.

Nazira Usmanova, DNP, psychiatric nurse practitioner at ORIGEN Healthcare

Your provider

Nazira Usmanova, DNP

Doctor of Nursing Practice, Board-Certified Nurse Practitioner, with more than 14 years of clinical experience. She sees children from age 2, teens and adults, and speaks English, Russian and Farsi.

  • Psychiatric Mental Health NP (PMHNP-BC)
  • Pediatric NP (CPNP-PC)
  • Adult-Gerontology NP (AGNP-BC)
Meet Nazira

“True healing comes from listening, understanding, and walking alongside my patients in their journey to wellness.”

Nazira Usmanova

Insurance we work with

We work with most major insurance plans. Coverage depends on your plan and the service, so our team checks your benefits with you before your visit.

Insurance and costs

Take the first step toward feeling better

You don’t have to figure it out alone. Tell us what is going on, and our care team will call you to find the right visit.

Mon to Fri, 9 AM to 5 PM12313 Gold St, Omaha, NE 68144